Processed mosaic of a sagittal section through the brain of mouse model
of glioma. To produce transformed cells, creGFAP mice were injected in
the cortex with Ras/s.i.p53 virus and perfused after 8 weeks. In this
system, GFP is introduced by the virus and expression is induced by an
IRES site in the mRNA. Thus, the GFP gene is expressed whenever the
virus infects a cell expressing GFAP (green). The section was
immunolabeled for GFAP (red) and counterstained with DAPI (blue). See
MP:8166 for a section from the same brain labeled with nestin.